منابع مشابه
Optogenetics: Applications in psychiatric research: Optogenetics for psychiatric research
Recently, optogenetic techniques have emerged as a method to optically manipulate molecular and cellular events in target cells both in vitro and in vivo. Optogenetics results from the fruitful combination of optics and genetic engineering, maximizing the advantages of each discipline. These advantages are optical control through the manipulation of wavelength and light intensity on the millise...
متن کاملOptogenetics for neurodegenerative diseases.
Neurodegenerative diseases are devastating conditions that lead to progressive degeneration of neurons. Neurodegeneration may result in ataxia, dementia, and muscle atrophies, etc. Despite enormous research efforts that have been made, there is lack of effective therapeutic interventions for most of these diseases. Optogenetics is a recently developed novel technique that combines optics and ge...
متن کاملOptogenetics and the circuit dynamics of psychiatric disease.
Optogenetics is a method for delivering millisecondprecision control (for activation or inhibition) to targeted cells using light within freely behaving mammals.1 The components of this method, as practiced today, involve (1) lasers and fiber optics for light delivery into the nervous system and (2) genes called microbial opsins, which encode light-activated proteins that regulate transmembrane...
متن کاملApplications of Optogenetics as Alternative Treatment for Neurological Diseases
Neurological diseases are some of the most devastating illnesses due to the limited understanding of the complex nervous system network and its intricate functions. Moreover, lack of basic understanding in pathophysiology of disease hinders the development of new treatment. Optogenetics is a biological technique involving light modulated cells in living tissue. Successful application of this te...
متن کاملPsychiatric diseases presenting as infectious diseases.
Although many psychiatric diseases have somatic manifestations, some focus on fears or delusions of infection. When a patient with a psychiatric basis for an apparent infection presents to an infectious disease physician, the physician may find the problem confusing, amusing, and ultimately frustrating until the psychiatric basis for disease is recognized. Some of these psychiatric disorders ca...
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ژورنال
عنوان ژورنال: Current Opinion in Neurobiology
سال: 2013
ISSN: 0959-4388
DOI: 10.1016/j.conb.2013.03.007